LL-37 is a synthetic peptide that researchers use in laboratory settings. The number 37 refers to the amino acids that make up its structure. Scientists often call this ll 37 peptide “Antibacterial protein LL-37” in their publications. This peptide is a tool for studying host defense mechanisms in controlled environments. Researchers look at its physical properties and how it behaves in solution. They also examine its structure under different laboratory conditions. Kimera Chems provides this material to research institutions. It is intended for laboratory investigations only.
Chemical Composition & Purity
The product comes as a white to off-white 5mg lyophilized powder. Its molecular formula is C₂₀₅H₃₄₀N₆₀O₅₃. The molecular weight of the substance is 4493.28 g/mol. CAS number 154947-66-7 identifies this specific compound. Kimera Chems verifies each batch for quality through third-party testing. They use high-performance liquid chromatography (HPLC) for analysis. This test confirms the peptide’s identity and purity. The purity level is ≥98% for research use. Analytical verification ensures each batch matches these exact specifications. Researchers use this data to confirm the chemical identity before starting any project.
Research Applications
LL-37 is used to study how peptides interact with lipid membranes. The mechanism starts with its positive charge. This charge pulls it toward negatively charged lipid heads on membranes. Once closed, its structure changes. Parts that avoid water insert into the lipid layer. This insertion can create openings or disturb the membrane organization. Researchers use it in different ways. All the research is performed in a controlled in vitro setting.
- Lipid Experiments: Added to artificial membranes to observe insertion and disruption.
- Shape Studies: Placed in different liquids to watch how it folds before membrane contact.
- Bacterial Tests: Mixed with bacteria in petri dishes to study membrane interactions.
- Cell Work: Added to immune cells growing in culture to watch binding events.
- Binding Tests: Used to measure how strongly it attaches to lipid molecules.
Storage & Handling Protocol
Proper storage keeps the peptide stable for research use. Follow these standard lab practices.
- Lyophilized peptides can be kept at room temperature, away from direct light.
- If reconstituted, the sample should be kept in the fridge.
- For long-term storage, the material must be stored in the freezer.
- Keep in a dry place with a desiccant.
- Keep the vial tightly closed.
- Handle with clean lab tools to avoid contamination.
Compliance & Usage Disclaimer
This product is for Research Use Only. It is not approved for human or animal consumption. It is not a medicine or dietary supplement. Any material offered as ll-37 peptide for sale is strictly for qualified institutions and professional investigators.
Availability & Research Sourcing
Kimera Chems is a reliable source for high-quality research materials. You can buy ll-37 or other premium chemicals from our website. We supply materials with the necessary analytical data to support your compliance needs.
| CAS Number | 154947-66-7 |
| Other Names | Antibacterial protein LL-37, Cathelicidin LL 37, GTPL5527 |
| IUPAC Name | (4S)-5-[[(2S)-6-amino-1-[[(2S,3S)-1-[[2-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S,3R)-1-[[(2S)-4-carboxy-1-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-1-oxobutan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-2-oxoethyl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-4-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]hexanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]-5-oxopentanoic acid |
| Molecular Formula | C₂₀₅H₃₄₀N₆₀O₅₃ |
| Molecular Weight | 4493.28 |
| Aliquot Concentration And Solution | Lyophilized Peptide 5mg |
