CL-316243 NMR
CL-316243 Article
CL-316243 Research Chemical
CL-316243 is a selective β3-adrenergic receptor agonist widely used in preclinical research involving metabolism, adipose tissue signaling, and energy expenditure. CL-316243 is sold strictly for research purposes only and is not approved for human or veterinary use.
What Is CL-316243?
CL-316243 is a synthetic small-molecule compound developed for laboratory research to selectively activate the β3-adrenergic receptor. This receptor subtype is primarily expressed in brown adipose tissue and plays a role in thermogenesis and lipid metabolism in animal models.
Mechanism of Action
CL-316243 functions by selectively binding to and activating β3-adrenergic receptors. Activation of these receptors has been shown in research models to:
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Stimulate lipolysis in adipose tissue
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Increase thermogenic activity in brown fat
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Enhance energy expenditure without strong β1 or β2 adrenergic stimulation
This selectivity makes CL-316243 useful in isolating β3-mediated metabolic pathways in controlled research environments.
CL-316243 in Research Studies
In animal studies, CL-316243 has been investigated for its effects on:
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Brown adipose tissue activation
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Fat mass reduction
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Glucose metabolism and insulin sensitivity
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Adrenergic receptor signaling pathways
Most published data involves rodent models, where β3-adrenergic receptor expression is more pronounced than in humans.
Research Applications
CL-316243 is commonly used in laboratory research focused on:
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Metabolic regulation
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Obesity and adipose tissue biology
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Thermogenesis and mitochondrial uncoupling
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β-adrenergic receptor pharmacology
Researchers utilize CL-316243 as a tool compound to better understand energy balance and fat metabolism mechanisms.
Important Research Disclaimer
CL-316243 is a research chemical intended for in vitro and in vivo laboratory research only. It is not approved for human consumption, medical use, or dietary supplementation. Proper laboratory handling procedures and ethical research standards must be followed at all times.
No product specifications available.
