ARA-290 is a synthetic peptide studied in laboratory settings as a specific 11-amino acid chain. Scientists identify this compound by the research name Cibinetide. It belongs to the helix B surface peptide (HBSP) family. This classification stems from its structural derivation from erythropoietin (EPO). Researchers buy ara 290 to investigate it for its interaction with a particular heteromeric receptor complex. This complex consists of the erythropoietin receptor (EPOR) and the beta common receptor (βcR). Scientists utilize cibinetide in various in vitro models to examine these molecular associations. The peptide serves as a primary tool for studying receptor-ligand specificity. It supports fundamental research in molecular biology and cellular signaling.
Chemical Composition & Purity
This product comes as a powder that has been lyophilized (freeze-dried). Scientists identify this substance by the molecular formula C₅₁H₈₄N₁₆O₂₁. It has a calculated molecular weight of 1257.4 g/mol. Ara 290 peptide appeared as a white to off-white solid substance. Every batch undergoes comprehensive analytical control to ensure consistency. Kimera Chems verify the purity using HPLC performed by a third party. This standard method confirms a purity of ≥98% for laboratory applications.
Research Applications
In laboratory science, ARA-290 is utilized as a selective research ligand. Its design is based on a specific region of the erythropoietin protein. Scientists study ARA-290 for its interaction with the EPOR/βcR receptor complex. Researchers evaluate it in in vitro models to examine binding to this receptor. This work focuses on understanding ligand-receptor associations in tissue protection signaling pathways.
- Receptor Binding Studies: For analyzing EPOR/βcR complex affinity.
- Cell Signaling Research: Use in models of tissue interaction pathways.
- In Vitro Model Systems: Application in neuronal or endothelial cell cultures.
- Comparative Ligand Analysis: Studying EPO derivative signaling.
- Pathway Mapping Studies: Researching non-hematopoietic receptor function.
Storage & Handling Protocol
Correct storage is essential to preserve the molecular stability of this lyophilized peptide. Scientists follow standard laboratory protocols to prevent degradation and maintain research viability.
- Lyophilized peptides can be kept at room temperature, away from direct light.
- If reconstituted, the sample should be kept in the fridge.
- For long-term storage, the material must be stored in the freezer.
- Keep in a dry place to prevent humidity.
- Store in amber vials or opaque containers.
- Keep the powder in tightly sealed vials.
Compliance & Usage Disclaimer
This product is for Research Use Only (RUO). It is not for human or animal consumption. It is not a medication, dietary supplement, or cosmetic.
Availability & Research Sourcing
Investigators looking for ara-290 peptide for sale can source this high-purity research chemical for their facilities from Kimera Chems. Certificates of analysis are provided to qualified customers to ensure the integrity of their research.
| CAS Number | 1208243-50-8 |
| Other Names | Cibinetide, ARA290, ARA 290, ARA-290, PHBSP, PH-BSP |
| IUPAC Name | (4S)-5-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-oxo-4-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoic acid |
| Molecular Formula | C₅₁H₈₄N₁₆O₂₁ |
| Molecular Weight | 1257.4 |
