What Is Fasoracetam?
Fasoracetam is a synthetic racetam-class compound originally investigated for its potential effects on cholinergic, glutamatergic, and GABAergic signaling pathways. Structurally distinct from older racetams, Fasoracetam contains a substituted pyrrolidone core that contributes to its unique physicochemical profile.
Within laboratory and academic environments, Fasoracetam has been studied for its interaction with metabotropic glutamate receptors (mGluRs), acetylcholine release modulation, and possible influence on GABA-B receptor activity. These characteristics have made it a compound of interest in advanced neurochemical research.
Fasoracetam Chemical Structure
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Chemical Name: (5R)-5-[(tetrahydrofuran-2-yl)carbonyl]pyrrolidin-2-one
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Molecular Formula: C₁₀H₁₅NO₃
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Molecular Weight: 201.22 g/mol
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Chemical Class: Racetam (pyrrolidone derivative)
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Stereochemistry: Chiral (R-enantiomer)
The pyrrolidone backbone is characteristic of racetams, while the tetrahydrofuran moiety differentiates Fasoracetam from compounds such as piracetam or aniracetam.
Physicochemical Properties
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Appearance: White to off-white crystalline powder
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Solubility: Soluble in water and polar solvents
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Stability: Stable under dry, cool, and light-protected storage conditions
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Hygroscopicity: Low to moderate
These properties make Fasoracetam suitable for precise analytical work and controlled experimental setups.
Mechanistic Research Overview
Preclinical research has explored Fasoracetam’s potential to:
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Modulate acetylcholine release
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Interact with mGluR signaling pathways
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Influence GABA-B receptor expression
Its multi-pathway profile distinguishes it from traditional racetams that primarily focus on cholinergic activity.
Common Research Applications
Fasoracetam is commonly referenced in research involving:
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Neurotransmitter signaling models
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Cognitive pathway investigations
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Synaptic plasticity studies
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Racetam structure-activity relationship (SAR) analysis
Its unique receptor interactions have made it valuable for comparative studies across racetam compounds.
Storage & Handling
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Store in a cool, dry environment
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Protect from moisture and direct light
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Seal tightly after handling
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For long-term storage, refrigeration is acceptable but not required if humidity is controlled
Product Quality & Verification
Each batch of Fasoracetam is:
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Independently tested for identity and purity
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Verified using analytical techniques such as HPLC and mass spectrometry
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Assigned a unique lot number for traceability
Research Use Disclaimer
This product is sold strictly for research and laboratory use only. It is not intended for human or veterinary consumption, diagnosis, treatment, or prevention of any disease.
| CAS Number | 110958-19-5 |
| Other Names | 110958-19-5, Fasoracetam [INN], N-(5-Oxo-D-prolyl)piperidine, NS 105, LAM-105, UNII-42O8UF5CJB, NFC1 ANHYDROUS, DTXSID9048855 |
| IUPAC Name | (5R)-5-(piperidine-1-carbonyl)pyrrolidin-2-one |
| Molecular Formula | C₁₀H₁₆N₂O₂ |
| Molecular Weight | 196.25 |
| Dry-Fill Capsule Concentration | 40mg |
